The oral bisphosphonates alendronate and risedronate and the selective oestrogen receptor modulator raloxifene increase BMD and decrease fractures in osteoporotic sufferers. Hormone replacement therapy increases BMD but its influence on fracture prevention is less clear. Calcitriol is no more recommended as first line treatment of osteoporosis.. An update on osteoporosis Simple strategies for preventing osteoporosis continue being underutilised, and a fitter elderly populace with higher individual bone mineral density may potentially decrease the incidence of morbidity because of osteoporosis. Assessment of bone mineral density by dual energy x-ray absorbtiometry continues to be the gold standard for analysis of osteoporosis. General lifestyle procedures in the management and prevention of osteoporosis include sufficient calcium intake, regular weight-bearing avoidance and exercise of smoking and unwanted alcohol intake.Other Johns Hopkins experts mixed up in scholarly research include Robert N. Adams, M.S.; Hee-Quickly Juon, Ph.D.; Alexei Miagkov, Ph.D.; and Yang Lu, Ph.D. Wenji Sunlight, Ph.D., of the University of Maryland now, done this study also.
Astex earns GBP5.9 M milestone payment from GSK for fragment-based screening platform Astex Therapeutics, the UK-based biotechnology firm developing targeted therapies for virology and oncology, announced that it has achieved multiple early milestones in its fragment-based drug discovery collaboration with GlaxoSmithKline which commenced in November 2009.