When compared with settings, the added risk was calculated as a hazard ratio of just one 1.33 for appendectomy and 1.44 for tonsillectomy. Dr Janszky, the study’s first author, emphasises that the absolute amounts of AMI cases in the analysis are small, with only slightly a lot more than 400 and 200 total situations of AMI in a lot more than 7.5 million and nearly 4 million person-years of follow-up. ‘As expected from the young age group of the populace,’ he says, ‘the noticed moderate boosts in relative risk in fact corresponded to really small risk raises in absolute terms.’ The investigators also note that the study population, despite its size, was limited to childhood exposure, with participants still relatively young at the end of follow-up.TYSABRI revenues increased 11 percent year-over-12 months to $269 million while AVONEX revenues increased 8 percent year-over-season to $703 million. RITUXAN revenues from our unconsolidated joint business set up had been $258 million for the quarter, approximately in-line with the last year. Global in-market product sales of TYSABRI in the 4th one fourth of 2011 were $380 million, a rise of 14 percent over the fourth quarter of 2010. The full total was made up of $196 million in U.S.